DNA Tests – How to Choose Which Ones to Use

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Why to consider the following questions when choosing a DNA test. Is the DNA test based on good science? Is the mutation associated with disease in your breed? Is information available regarding the disease-associated risk of each genotype? Is information available regarding the mode of inheritance? Is information available regarding the prevalence of the disorder or the frequency of the mutation in my breed? What are you going to do with the results? How will the results affect my breeding decisions? Has the DNA testing laboratory got a good reputation for accuracy and for a willingness to help resolve queries? Does the lab have ISO accreditation? Was the testing laboratory involved with the research to identify the mutation?

Mellersh, C. (2015). DNA tests: How to choose which ones to use. In Tufts’ Canine and Feline Breeding and Genetics Conference, 2015. Dedham, MA; Cummings School of Veterinary Medicine, Tufts University. https://www.vin.com/apputil/content/defaultadv1.aspx?pId=12513&meta=Generic&catId=51025&id=6976373&ind=19&objTypeID=17.

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Topic(s): Breeder Resource, Genetic Counseling, Genetics